The effect of herbal medcinal plants on the proteus species resistance against antibiotics

Document Type : Original Article

Authors

1 Department of Botany, Faculty of Science, Mansoura University, Mansoura, Egypt

2 Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Abstract

Proteus mirabilis is a gram-negative member of the Enterobacteriaceae family of bacteria. Numerous infections, including those of the respiratory tract and urinary tract, are caused by it. High antibiotic resistance in Proteus mirabilis may result in multidrug resistance and the failure of antimicrobial therapy. Objective: The current paper's objective is to investigate the possible antibacterial properties of medicinal plants as well as their value as a source of new anti-infection chemicals. Results: Twenty-five proteus isolates, recorded resistance to different antibiotic categories. The highest resistance was shown to trimethoprim-sulfamethoxazole (96%), the highest intermediate was shown to imipenem (28%) and the highest susceptibility was shown to Piperacillin-tazobactam (88%). The diameter of the inhibition zone of ethanolic extracts was tabulated for all extracts, the ethanolic exteract of  green tea was the most active with an inhibition zone diameter (mm) ranged between 25 and 40, followed by clove with inhibition zones diameter ranged between 23 and 31. Followed by  lemon and cinnamon respectively but the ginger was the most inactive one with inhibition zone diameter (mm) ranging between 0 and 14. Based on the results obtained during this study, we recommend the application of some medicinal plants like Camellia sinensis (green tea) against antibiotic resistant Proteus species isolated from patients admitted to Mansoura University Hospitals.

Keywords

Mansoura Journal of Biology
Volume 62, Issue 1
March 2023
Pages 23-34

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