Immunological Studies on Systemic Lupus Erythematosus

Document Type : Original Article

Authors

1 Department of Botany, Faculty of Science, Mansoura University, Egypt

2 Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Egypt.

3 Rheumatology and immunologyUnit. internal department Faculty of medicine

Abstract

Abstract:The main work of this study was the Immunological Studies on Systemic Lupus Erythematosus collected from different patients admitted to Mansoura hospitals. Then, this study was to define the disease through stereotyped diagnosis by detecting antinuclear antibodies (Anti-ds-DNA, ANA) by ELISA of samples collected from patients diagnosed with systemic lupus erythematosus in Immunology and Rheumatology Clinics of University Hospital Mansoura in Egypt. Systemic lupus erythematosus is an autoimmune disease in which the immune system attacks various organs and tissues of the body such as the kidneys, heart, lungs, brain, blood and skin. 50 samples (66.7%) were positive for ANA, while there were 25 samples (33.3%) were negative for ANA, while all samples were 100% positive for Anti-ds-DNA using ELISA.

Keywords