Effect of growth hormone on female infertility

Document Type : Original Article

Authors

1 Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt

2 Biology Department, Faculty of Science, Al-Farabi University college, Baghdad, Iraq

3 High Institute for Infertility Diagnosis and ART, Al-Nahrain University, Baghdad, Iraq

4 Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Abstract

One in six couples suffers from infertility, which is a common problem. It is defined as the failure to conceive following a reasonable period of sexual intercourse without the use of contraception.  Growth hormone (GH) regulates male and female fertility and has been used to treat both male and female infertility. In addition to the pituitary gland, the ovary produces GH. Monofollicular growth is aided by GH. GH therapy is a treatment that is used as an adjuvant in ovarian stimulation and Assisted Reproductive Techniques (ART). GH supplementation has been shown to increase pregnancy rate in women with poor ovarian response. Growth hormone therapy plays a role in ovarian stimulation and has beneficial efficacy in carefully selected cases. The study’s main goal was to look at the influence of growth hormone on the implantation process in women who had a poor ovarian response after intracytoplasmic sperm injection. The Baghdad IVF Center in Baghdad, Iraq, was home to 90 infertile women with poor ovarian response (POR). The women's ages ranged from 35 to 45. The BMI (body mass index) was calculated. On the day of ova collection, growth hormone levels were measured in both the follicular fluid and the serum. ICSI procedure was used and recorded the pregnancy status. Growth hormone levels were statistically insignificant between pregnant and non-pregnant cases on the day of ova pick up and embryo transfer.

Keywords

Mansoura Journal of Biology
Volume 55, Issue 2
June 2022
Pages 29-36

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