Biocontrol of Proteus causing Urinary Tract Infection: Morphological and Biochemical Studies

Document Type : Original Article

Authors

1 Department of Botany, Faculty of Science, Mansoura University, Mansoura, Egypt

2 Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

10.21608/mjb.2022.459815

Abstract

Urinary tract infection (UTI) is a illness initiated by bacteria such  as Proteus spp.Various antibiotic medications can be used to treat UTIs.  Antibiotic  resistance  has  unfortunately  increased  and  is  now  a  hazard  to  public health. The  purpose of  this study was to  look  for  Proteus  spp.  that  were  multi-drug resistant (MDR).Fifty isolates of the Proteus spp. were  isolated and then identified. strains isolated from patients in Mansoura  University Hospitals, Mansoura City, Egypt, because of  their  importance  for  treating infections in people. By using morphological and biochemical  methods. Their antimicrobial vulnerability to 11antimicrobial agents from 8  antimicrobial categories (aminoglycosides, penicillins, carbapenems,  cephalosporins, fluoroquinolones, penicillins/ß-lactamase inhibitors,  quinolone, diaminopyrimidines) was determined  by  the  disc diffusion  method, according  to the reference of the  medical  and  Laboratory  tandards  Institute. Isolates  of  Proteus  spp.  were  classified  as  MDR in accordance with standardized  international  terminology, which  was  presented  by  the  European  Centre  for  Disease Prevention  and  Control. Medicinal  plants  proved  high  effectiveness  in  treating  UTI with  no  side  effects  especially  clove.  the  ethanolic  extract  of  clove  was  the  most  active  one  with  inhibition  zones  diameter  ranged  between  (14mm  –  25  mm).

Keywords

Mansoura Journal of Biology
Volume 61, Issue 8
December 2022
Pages 58-63

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