Microbiological and Immunological Studies on Type I Diabetes Mellitus Patients

Document Type : Original Article

Authors

1 Professor of Applied Microbiology, Botany Department, Faculty of Science Mansoura University, Egypt.

2 Children's University Hospital, Faculty of Medicine, Mansoura University

3 Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

10.21608/mjb.2021.460018

Abstract

Type 1 diabetes mellitus is the most common chronic condition in children, although it can strike anyone at any age. T1DM has been steadily increasing in incidence and prevalence, accounting for about 5% to 10% of all diabetics. Environmental factors such as dietary variables, endocrine disruptors and other environmental pollution, and gut microbiome composition have all been linked to type 1 and type 2 diabetes. Obesity and insulin resistance, in addition to their well-known involvement in type 2 diabetes, may act as type 1 diabetes accelerators. In contrast, in a fraction of persons diagnosed with type 2 diabetes, islet autoimmunity linked to probable environmental factors (e.g., food, infection) may play a role.

Keywords