Antimicrobial activity of some herbal plant extract against urinary tract microorganisms

Document Type : Original Article

Authors

1 Department of Botany, Faculty of Science, Mansoura University, Mansoura, Egypt

2 Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

10.21608/mjb.2021.460281

Abstract

Urinary tract infection (UTI) is the second well- known cause of infection, which invades the human body. Globally, an estimated number of 150 million infections are found in the urinary tract yearly. UTI is a disease caused by bacteria such as E. coli and fungi such as Candida, which impacts the urinary tract. UTI can be treated by different antimicrobial agents. Unfortunately, the evolution and spread of antibiotic and antifungal resistance have become a threat to public health, compromising the treatment of bacterial and fungal infections. Thus, it is crucial to find alternative treatments such as herbal medicine to cure the human infectious diseases caused by E. coli and Candida. Medicinal plants proved high effectiveness in treating UTI, with no side effects especially cinnamon. Antimicrobial activity of cinnamon was probably due to its oil as well as the pure cinnamaldehyde. There are ten chemical components of cinnamon oil. The main components were eugenol and eugenyl acetate It was reported that eugenol and eugenyl acetate were the major bioactive constituents of the  cinnamon oil. These volatile phenolic compounds could disrupt the membranes of microberial cells, leading to the cell death.

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